Asymmetry test of EGGER

Asymmetry test of EGGER

•Linear regression approach to measure funnel plot asymmetry on the natural logarithm scale of the odds ratio

•The standard normal deviate (SND), defined as the odds ratio divided by its standard error, is regressed against the estimate's precision, the latter being defined as the inverse of the standard error 

•(regression equation: SND= a+ bxprecision)

•As precision depends largely on sample size, small trials will be close to zero on the × axis

•Null hypothesis –symmetry exists in the funnel plot

PSM / COMMUNITY MEDICINE by Dr Abhishek Jaiswal is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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